A Brain-Based Endophenotype for Major Depressive Disorder

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

A brain-based endophenotype for major depressive disorder.

We have identified a brain-based endophenotype for major depressive disorder (MDD) that includes thinning of the cortex of the lateral aspect of the right hemisphere and the medial aspect of the left, as well as bilateral hypoplasia of frontal and parietal white matter. The endophenotype status of these abnormalities is supported by their presence in a multigenerational cohort of persons who th...

متن کامل

Phonologically-based biomarkers for major depressive disorder

Of increasing importance in the civilian and military population is the recognition of major depressive disorder at its earliest stages and intervention before the onset of severe symptoms. Toward the goal of more effective monitoring of depression severity, we introduce vocal biomarkers that are derived automatically from phonologically-based measures of speech rate. To assess our measures, we...

متن کامل

Vortioxetine versus placebo for treatment of major depressive disorder

Introduction: Major depressive disorder is a common mental condition associated with substantial morbidity and economic burden. Approved by the FDA in September 2013 for treatment of episodes of major depressive disorder, Vortioxetine is one of the newer options available in this important area of therapeutics. Materials and methods: A comprehensive literature search (PubMed, the Cochrane libr...

متن کامل

Sheehan’s Syndrome Presenting as Major Depressive Disorder

Sheehan’s syndrome or Simmond’s disease is a rare endocrine disorder seen in clinical practice. The clinical spectrum is diverse and a high index of suspicion together with a good clinical acumen and proper diagnostic approach helps in early diagnosis and prompt treatment of this endocrinopathy. Sheehan’s syndrome presenting as a major depressive disorder finds less mention in the literature.Th...

متن کامل

Brain Circuits in Major Depressive Disorder and Bipolar Disorder

The lifetime prevalence rates of unipolar depression (UPD) in males and females of first-world countries are approximately 15 and 25 percent, respectively. The figures appear to be equally disheartening in developing countries: The 12-month prevalence of major depressive disorder in South Africa is roughly 5 percent. It is therefore not surprising that 25 percent of all visits to health care pr...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Annual Review of Medicine

سال: 2011

ISSN: 0066-4219,1545-326X

DOI: 10.1146/annurev-med-010510-095632